ProBiotic Multi-Strain Pro22 is a powerful probiotic with added Prebiotic Pro-Flora. For individuals with digestive upset such as irregularity probiotics may be of benefit. Probiotics are a natural way to help balance the body's internal bacterial environment. Probiotic effectiveness can aid with acute diarrhea, traveler's diarrhea and upset stomach. These healthy bacteria help us properly digest our food, protect us from pathogens (harmful microorganisms), help us detoxify harmful compounds, produce vitamins and other nutrients and benefits our immune systems. But if you are to begin taking this type of all natural supplement, what should you be looking for? Well, first, you are looking for a mix of strains of bacteria, most notably different strains of Lactobacillus and Bifidobacterium, often on labels as "L." something and "B." something.Those are the strains that have the most benefit to the human intestinal tract. One way to determine whether a particular supplement is of high quality is to see if the strains are purified, genetically characterized and registered, and this is most often demonstrated by letters and numbers listed after the name of the strain (such as La-14 or Bl-04). The next most important factor is just how much bacteria is in the supplement? This amount is often measured in CFU (Colony Forming Units), which is also the same thing as the Number of Organisms expressed in billions. There is no set dosage, as each person's internal environment is different; however, very low dose supplements of 1 to 2 billion organisms are less likely to have a beneficial effect than supplements with 10 - 20 billion organisms. ProBiotic Pro-22 contains over 20 billion organisms, and it is shelf-stable and does not require refrigeration.