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The macular region of the human retina is yellow in color due to the presence of the macular pigment composed of two dietary xanthophylls lutein and zeaxanthin and another xanthophyll meso-zeaxanthin. The latter is formed from lutein in the retina (1).Scientists long ago discovered that the carotenoids lutein and zeaxanthin help protect the macula and photoreceptor outer segments throughout the retina from photo-initiated oxidative damage. New research has discovered that a third carotenoid meso-zeaxanthin is required by the aging macula to maintain its structural density.Protecting Your Macular DensityBy absorbing blue-light the macular pigment protects the underlying photoreceptor cell layer from light damage. The density of your macular pigment (composed of lutein zeaxanthin and meso-zeaxanthin) is essential to proper vision. Unfortunately this density declines naturally over time. Patients with macular degeneration have been shown to have 30% less meso-zeaxanthin in their macula compared to healthy eyes (2). One reason for this deficiency of meso-zeaxanthin is lack of ingested lutein.
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