Biotics Research Iodizyme-HP the use of oral iodine/iodide can aid in circumventing this issue. As a result of decreased iodine status, due to the typical Western diet, sufficient thyroxine cannot be produced, negatively impacting thyroid function. Published information suggests iodine/iodide helps to maintain healthy hydroxyl estrogen ratios as well. Iodine is an essential trace mineral necessary for the production of thyroxine (T4). Although approximately 80% of the dietary intake of iodine is sequestered by the thyroid gland, other tissues concentrate iodine as well. They include salivary glands, the gastric mucosa, the choroid plexus, mammary glands, and the ovaries. However, iodine is often found lacking in the typical western diet. Consequently, as a result of decreased iodine status, sufficient thyroxine cannot be produced by some, negatively impacting thyroid function. Interestingly, published information suggests iodine/iodide helps to maintain healthy hydroxyl estrogen ratios. Fibrocystic breasts, uterine fibroids, ovarian cysts, joint degeneration, fatigue, and impaired immune function have all been linked to iodine deficiency.